This is new guidance from NICE advising that dapagliflozin can be used for certain patients with CKD. This was released in March 2022.
In July 2025 the guidance was updated to broaden the conditions in which we can use dapagliflozin. This is to bring it in line with the criteria used for empagliflozin. Dapagliflozin and empagliflozin haven’t been directly compare in studies, but the indirect evidence suggests that they are both equally effective and safe.
When can dapagliflozin be used to treat chronic kidney disease (CKD)?