Dapagliflozin with insulin for patients with Type 1 Diabetes

11th October 2019 by Louise Hudman

Dapagliflozin with insulin for patients with Type 1 Diabetes

This is a new guideline from NICE on using dapagliflozin in patients with Type 1 diabetes. It was published in Aug 19.

Key learning points for me:

  • There is a rise in the risk of ketoacidosis.
  • It needs stopping if there is a sustained fall in GFR to < 45.

The main concern with using dapagliflozin alongside insulin in patients with Type 1 diabetes (T1DM) is that there is an almost two-fold rise in the risk of diabetic ketoacidosis. However the absolute risk is not that high. Because of this, quite rigid restrictions have been placed on who is eligible.

Read for free

Sign up to access everything.

Free trial

Login

Already a member? Login to view this content.

Login

Related content

"LocumDeck is so good and so intuitive that I am lost for words and utterly filled with glee.

It can send an email confirming the sessions that are booked and creates and emails invoices direct to the practice for you. These contain links to your beautifully laid out ‘credentials’ page with all your relevant documents, and a model contract that is all ready for you to accept or edit.

It automatically produces and sends the locum form A, and will produce locum form B. It also acts as the calendar... And it all happens automatically. It is really less than a minute to invoice and do the pension forms, with everything calculated perfectly."

Dr Annette Steele

See the full list of features within our NASGP membership plans

Membership