This is guideline from NICE on a newly recommended treatment for chronic idiopathic constipation.
The medication is Lubiprostone, which works by activating chloride channels in the GI tract, thus increasing intestinal secretions and improving constipation.
It has a different method of action to prucalopride, which NICE released guidance on in 2011. Lubiprostone is more cost-effective than prucalopride.