Investigation and management of antiphospholipid syndrome

12th April 2012 by Louise Hudman

Most of this guideline is aimed at specialists. However it is a useful overview for us. I am summarising the things that we need to be aware of.

Antiphospholipid syndrome (APS) can be secondary (eg to SLE or Rheumatoid Arthritis) or primary. Diagnosis isn’t based on rigid criteria, but generally a patient must have had either a thromboembolic event (venous, arterial or microvascular) or an adverse pregnancy outcome (recurrent miscarriage, pre-eclampsia or placental insufficiency). They must also have positive antibody tests (lupus, anticardiolipin or anti-b2-glycoprotein I).

Who should be investigated?

  • Unprovoked promixal DVT or PE. Leave at least 1/52 post anticoagulation.
  • CVA (ischaemic)  if under age 50.
  • Miscarriage – if ≥ 3 (normally done by referral to recurrent miscarriage clinic).

Join

Join to view the rest of this content, as well as access all the benefits of joining NASGP.

Join

Login

Already a member? Login to view this content.

Login

"I am so glad and grateful for being a member of NASGP's BOB locum chambers. I started with them in a critical period of my career as I was a newly-qualified GP, looking for work in a new area with a new virus hardly hitting the world and the jobs market.

Richard and Ali's help was a godsend. They introduced me to locum work in a friendly and kind manner, provided valuable support and excellent service through the ever-improving LocumDeck and NASGP website. With the help of the chambers, I received a face to face tutorial on Emis (I trained on SystmOne) and my online profile was promoted on a growing network of GP practices throughout Buckinghamshire, Oxford and Berkshire.

I was able to work in different GP practices with different staff and patient demographics, massively increasing my clinical experience, resilience and communication skills.

It also helped me funnelling down all the job offers I received through my locum work until I recently agreed for a salaried position in a GP practice that I love working at. "

Dr Nazar Ahmed

See the full list of features within our NASGP membership plans

Membership