Icosapent ethyl and high triglyceride (TAG) levels (Nice, 2022)

27th August 2022 by Dr Louise Hudman

Icosapent ethyl and high triglyceride (TAG) levels (Nice, 2022)

Icosapent ethyl is used for secondary prevention of cardiovascular disease in patients with high triglyceride (TAG) levels.

This is a new guideline from Nice on using icosapent ethyl in patients with high TAG levels, published on 13 July 2022.

Icosapent ethyl is recommended as an option for reducing the risk of cardiovascular events in adults who:

  • have raised TAG ≥ 1.7mmol / L AND
    • who are taking statins AND
      • LDL > 1.04 mmol/L and ≤ 2.6 AND
        • have established cardiovascular disease defined as a history of any of the following:
          • ACS (MI or unstable angina needing hospitalisation).
          • Coronary or other arterial revascularization.
          • Coronary heart disease.
          • Ischaemic stroke.
          • Peripheral arterial disease.

If a patient can not tolerate a statin, can they still use icosapent ethyl?

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