This is a monster of a guideline from NICE, which is only aimed at people over the age of 12. This email contains the summary, but if you want to read more, then use the link at the bottom.
My main feeling about this guideline, having trawled though the 360 pages of evidence, is that it is more a summary of what we currently know, than a guideline. They exclude commonly used treatments like amitriptyline and pizotifen from the guideline, not because there is evidence that they are ineffective, but because the studies just haven’t been done yet. A lot of the evidence that is available, is of poor quality and is often contradictory.
From my personal point of view, this guideline will not be changing my practice much.
