This is a new guideline from NICE advising that rivaroxaban plus aspirin can be used in the prevention of atherothrombotic events, under certain circumstances. It was published in Oct 2019. This is quite a big change in practice.
Rivaroxaban can be used together with aspirin as an option for the prevention of atherothrombotic events in adults with
Coronary artery disease OR symptomatic peripheral artery disease…
…those who are at high risk of ischaemic events:
- Aged 65 or over OR
- Have atherosclerosis in at least 2 areas (eg coronary, cerebrovascular or peripheral arteries) OR
- Have 2 or more of the following risk factors:
- current smoking
- CKD with eGFR < 60
- heart failure
- previous non-lacunar ischaemic stroke.