e-learning | New treatments for hyperkalaemia

7th May 2020 by Dr Louise Hudman

e-learning | New treatments for hyperkalaemia

There have been two recent new guidelines from NICE on managing hyperkalaemia. The first deals with the snappily named sodium zirconium cyclosilicate. The second deals with patiromer. These are both oral drugs, binding potassium in the GI tract and, as they are not absorbed, it is then excreted.

Who can have these drugs?

Both drugs have the same recommendations. They can be used alongside the standard treatments in emergency care of patients with hyperkalaemia. More importantly for us, they can be used in outpatient care if they have persistent hyperkalaemia and:

  • have CKD stage 3b to 5 OR chronic heart failure AND
  • have K+ of at least 6 mmol/L AND
  • are not taking an optimised dose of a drug that acts on the renin-angiotensin-aldosterone system (RAAS) because of their hyperkalaemia AND
  • are not on dialysis.

Do they work?

There is no evidence that these drugs extend life, nor that they improve quality of life. However, the thinking is that if they allow people to take a higher dose of the RAAS inhibitors or to stay on them longer, that may extend life and improve quality of life.

Read more

No credit card details needed – it takes two minutes.

Join free trial


Already a member? Login to view this content.


"I started working as a locum GP in January this year and NASGP have been invaluable in helping to co-ordinate my bookings and organise all the administrative aspects of sessional work which can be complex and time consuming. Their client support is outstanding and they have always resolved any queries promptly and personally. They care about the service they provide and I would not hesitate to recommend them to any sessional GPs who want to minimise time spent on administration and focus on providing patients with high quality care."

Dr Paul Riley, GP

Dr Paul Riley, GP

See the full list of features within our NASGP membership plans