Vibegron in overactive bladder syndrome (Nice, 2024)

Like Mirabegron, Vibegron is also a beta-3 adrenergic receptor agonist.

Repurposing: the risks and rewards of thinking again

Primary care could exploit repurposing strategies: Medical prescribing is appropriate for medical problems, but many GPs are frustrated that they can’t adequately address the social problems which afflict so many people.

Daridorexant for treating insomnia (Nice, October 2023)

Dr Louise Hudman summarises a new guideline for sleep, published in October 2023.

Tirzepatide subcutaneous injection for type 2 diabetes

Learn how this once-weekly subcutaneous injection is prescribed.

Progesterone-only pills (POPs) advice (FRSH, 2022)

This is an updated guideline from FSRH on POPs published in Aug 2022.

Inclisiran for lipid modification in GP (Nice, 2021)

There haven’t been any direct comparisons between inclisiran and ezetimibe, alirocumab or evolocumab yet.

C.diff and antimicrobials in GP (2021 update)

NICE's July guideline updates GPs' prescribing guidance.

Contraceptive prescribing for people with eating disorders

A new statement from FSRH outlines some of the issues surrounding contraceptive choice for people with eating disorders.

Antimicrobial prescribing for human and animal bites

A new guideline from NICE covers the prescribing of antibiotics for human and animal bites.

Prescribing

Fremanezumab for preventing migraine

Although fremanezumab seems to be effective in episodic migraine, it hasn't been approved as it isn't felt to be cost-effective

e-learning | Sotagliflozin with insulin for type 1 diabetes

A new guideline from NICE from February 2020 advises that sotagliflozin can be used alongside insulin for type 1 diabetes

e-Learning | COPD – antibiotic prescribing in an acute exacerbation

The most interesting bit for me about this new guideline was that only 50% of COPD exacerbations are thought to be caused by bacterial infections. The rest are caused mainly by viral infections or smoking.

e-Learning | Coughs (of the acute kind) and antimicrobial prescribing

This is a new guideline from NICE on when to prescribe antibiotics for coughs. It only covers those with acute coughs and doesn't include COPD patients (they are covered in a separate guideline).

Levosert – a levonorgestrel intrauterine device (LNG-IUS)

This is a new product review from the FSRH. Levosert is an LNG-IUS, which is the same as Mirena.

Podcast | A viper’s nest: when venom is a man’s best friend

Did you know that captopril was derived from the venom of the deadly Brazilian pit viper? Since it went on the market in 1981 captopril and its successor ACE inhibitors have probably saved many more lives than have been lost to pit vipers.

The doctor’s bag

Nice | Idelalisib for treating chronic lymphocytic leukaemia

Nice | Empagliflozin in Type 2 Diabetes

FSRH | Depot contraception

Nice | Rivaroxaban in Acute Coronary Syndrome (ACS)

Nice | Vitamin D supplementation

Prescribing

Raising concerns about poor prescribing

Drug allergy: diagnosis and management in GP

Nice | Lubiprostone for treating chronic idiopathic constipation

FSRH | St John’s Wort and contraceptives

Nice | New treatments for BPH, MS and migraine

NSAIDs

Nice | Neuropathic pain

FSRH | Emergency contraception in obese women

Nice | MI secondary prevention

Nice | Rivaroxaban for treating PE and preventing recurrent embolism

Zoely – A new Combined Oral Contraceptive (COC) pill

Omalizumab in severe allergic asthma

FSRH | Ella-One and new drugs interacting with contraceptives

Apixaban in Atrial Fibrillation

Ivabradine in Heart Failure

Esmya and Contraceptives

HRT – it’s good for the heart

Nice | Rivaroxaban for DVT treatment

Prescribing for shrimps

Nice | Venous thromboembolism (DVT) investigation and management

Botulinum A for migraine

Read GP financial advice on setting up a self asessment tax account for sessional GP work, starting out as a GP locum, how IR35 affects your GP locum, whether to join, stay or leave the NHS Pension Scheme, and what allowable expenses GP locums should record in their annual tax return.

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