Nice | Mirabegron for overactive bladder syndrome (OAB)

This guideline looks at a new drug, Mirabegron. It can be used for frequency, urgency and incontinence in OAB, if antimuscarinics are not suitable, or are not effective. They do advise that it's use should be seen as part of a treatment pathway, including bladder retraining.

It is a beta-3 adrenoreceptor agonist, which activates the receptors to allow the bladder to relax, allowing it to store more urine.

Louise Hudman

I'm a freelance GP locum in Winchester & Southampton locum chambers, and Pallant Medical Chambers Clinical Guidelines Lead Partner.

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