fbpx

Kyleena – a new intrauterine system for contraception

This is a statement from Jan 18 from FSRH giving information about Kyleena, which is a new levonorgestrel (LNG) containing intrauterine system (IUS).

What is Kyleena?

An IUS. It contains levonorgestrel, like Mirena does.

It is licensed for 5 years of use, but only for contraception. It is not licensed for use in heavy menstrual bleeding, nor for the progesterone component of HRT.

What other IUS are there?

The statement has a good table comparing the different coils. Some of the key features are below:

  • Mirena - total 52mg of LNG. Released at 20mcg/24 hr. Lasts 5 years. Bigger.
  • Kyleena - total 19.5mg of LNG. Released at 17.5mcg/24 hrs. Lasts 5 years. Smaller.
  • Levosert - total 52mg of LNG. Released at 20mcg/24 hrs. Lasts 3 years. Bigger.
  • Jaydess - total 13.5mg of LNG. Released at 14mcg/24 hrs. Lasts 3 years. Smaller.

How does it compare to the other IUS?

Contraceptive efficacy, side-effect profile and adverse events are all similar to the other IUS.

What are the advantages?

It has a narrower insertion tube and a smaller frame than Mirena and Levosert, which may be preferable for some women.

Studies suggest that it is easier to insert than Mirena and with less pain caused. Jaydess is similar in this regard.

Cost. It is the cheapest per year (£15.2 per year compared to £17.6 per year for Mirena).

What are the disadvantages?

The limited licensing (ie only for contraception).

Bleeding. It is possible that it brings more bleeding / spotting days than Mirena and Levosert, but this didn't reach statistical significance in the trials. It is possible that the rate of amenorrhoea is lower than with Mirena (again this wasn't statistically significant in the trials). The rate of amenorrhoea is about 18.9% at 3 years.

I’m a freelance GP locum in Winchester & Southampton.

NEW! – Use the NASGP CPD templates to record your reflections.

No Comments Yet.

Leave your comments