Recent Posts by Louise Hudman

Nice | Who should we be testing for cirrhosis?

This is a new guideline from NICE on cirrhosis. The most important bit for us is knowing who should be tested as we may need to be referring these patients on. Higher risk patients Hepatitis B Hepatitis C Misuse of alcohol BMI of 30 or more Type 2 diabetes Who should be tested for cirrhosis?…
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Nice | Non-alcoholic fatty liver disease NAFLD

This is a new guideline from NICE on non alcoholic fatty liver disease (NAFLD) in children, young people and adults. To be honest, I don't think this guideline is terribly helpful. I've done a brief summary, then more detailed notes. In summary: Adults There is no advice on who to test to diagnose NAFLD, nor…
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Evolocumab and Alirocumab for treating dyslipidaemia

There are two new guidelines from NICE on the use of Evolocumab and Alirocumab for treating primary hypercholesterolaemia (both familial and non-familial) and mixed dyslipidaemia. What are these drugs? Both Evolocumab and Alirocumab are monoclonal antibodies that inhibit an enzyme that down-regulates LDL receptors. This therefore increases the number of LDL receptors and so increases…
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Nice | Non-alcoholic fatty liver disease NAFLD

This is a new guideline from NICE on non alcoholic fatty liver disease (NAFLD) in children, young people and adults. To be honest, I don't think this guideline is terribly helpful. I've done a brief summary, then more detailed notes. In summary: Adults There is no advice on who to test to diagnose NAFLD, nor…
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Nice | Detection and management of sepsis

This is a new guideline from NICE on the detection and management of sepsis. None of this is likely to be new, but it is worth looking through. I think the main reason is, sadly, from a medico-legal point of view. I guess if we have not documented obs that have been clearly laid out,…
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Nice | Alzheimer’s drugs

This is a guideline update from NICE on the use of  donepezil, galantamine, rivastigmine and memantine in Alzheimer's disease. Donepezil, galantamine and rivastigmine (the acetylcholinesterase - AChE - inhibitors) can now be used in mild disease, as well as in moderate disease. These drugs all work by increasing the level of ACh at sites of…
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